I didn't like it. I felt that several of the characters lost some of their appeal and essence by having their genders switched. For example, Emmet, who for me is the lovable, protective big brother, just didn't translate as well as a female and everything I loved about the character was stripped away. Beau was even more bland than Bella’s character, and lacked a strong male voice. I think Charlie, one of two characters whose gender was not altered, is probably the only character that was recognizable.
Readers should also be prepared for some serious plot changes. Life and Death is definitely a reimagining and not a retelling. I'm glad Meyers made the changes she did because it ensures that there will be no continuations of this story line, which I wouldn't read even if there were.
This reimagining certainly didn't diminish my love for the original, but I'm hoping that when Twilight turns 20 that Meyers will give her fans what we really want...Midnight Sun.